JUPITER, Fla., Nov. 12, 2025 (GLOBE NEWSWIRE) -- Dyadic International, Inc. ("Dyadic", "we", "us", "our", or the "Company") (NASDAQ:DYAI), d/b/a, Dyadic Applied BioSolutions, a global biotechnology company producing precision- engineered, animal-free proteins and enzymes for diverse commercial applications, today reported its financial results for Q3 2025 along with significant corporate achievements.

"During the third quarter, Dyadic completed its strategic pivot from a research and development-driven company to a commercially focused biotechnology solutions provider underpinned by our protein production platforms," said Joe Hazelton, President and Chief Operating Officer of Dyadic. "With our comprehensive rebranding, redesigned website optimized for commercial engagement and investor relations, and the addition of CRISPR technology through our ERS Genomics license, we are strengthening the foundation for scalable growth."

Mr. Hazelton concluded, "Our third-quarter achievements demonstrate the successful execution of our strategic transformation to a commercial biotech leader. With enhanced capabilities from our CRISPR license, growing commercial traction, and a strengthened financial foundation, we believe Dyadic is well positioned for sustainable revenue growth and long-term value creation."

Recent Operational Highlights Corporate Development

Life Sciences

Food and Nutrition

Bio Industrial Products

Biopharmaceutical Programs

Financial Highlights

Cash Position: As of September 30, 2025, cash, cash equivalents, restricted cash and cash equivalents, and the carrying value of investment-grade securities, including accrued interest, were approximately $10.4 million compared to $9.3 million as of December 31, 2024.

On August 1, 2025, the Company completed an underwritten offering (the "Offering") of 6,052,000 shares of its common stock, par value $0.001 per share, at a public offering price of $0.95 per share. The net proceeds to the Company from the Offering were approximately $4.9 million, after deducting legal expenses, underwriting discounts and commissions and other offering expenses. The Company intends to use the net proceeds of the Offering for working capital and general corporate purposes, such as product development, sales and marketing.

Revenue: Total revenue for the three months ended September 30, 2025, decreased to $1,165,000 compared to

$1,958,000 for the same period a year ago. The decrease was due to decreases in research and development revenue of $183,000, driven by a reduction in the number of active collaborations, and license and milestone revenue of $1,425,000 from the Proliant agreement and Inzyme agreement for the same period a year ago. The decrease is offset by an increase in grant revenue of $815,000 from the Gates Foundation and CEPI grants in 2025.

Cost of Revenue: Cost of research and development revenue for the three months ended September 30, 2025, decreased to $255,000 compared to $396,000 for the same period a year ago. For the three months ended September 30, 2025, cost of grant revenue from the Gates Foundation and CEPI grants was $769,000, compared to $0 for the same period a year ago.

R&D Expenses: Research and development expenses for the three months ended September 30, 2025, increased to $572,000 compared to $460,000 for the same period a year ago. The increase was driven by a rise in the number of active internal research initiatives undertaken to expedite product development.

G&A Expenses: General and administrative expenses for the three months ended September 30, 2025, increased to $1,481,000 compared to $1,298,000 for the same period a year ago. The increase reflected increases in rebranding and business development expenses of $176,000, legal and accounting expenses of $83,000, and other expenses of $3,000, offset by a decrease in share-based compensation expenses of $79,000.

Loss from Operations: Loss from operations for the three months ended September 30, 2025, increased to $1,925,000 compared to $203,000 for the same period a year ago.

Net Loss: Net loss for the three months ended September 30, 2025, increased to $1,976,000 or $(0.06) per share compared to $203,000 or $(0.01) per share for the same period a year ago.

Conference Call Information

Date: Wednesday, November 12, 2025

Time: 5:00 p.m. Eastern Time

Dial-in numbers: Toll Free: 1-877-407-0784 or 1-201-689-8560 (International)

Conference ID: 13751389

Webcast Link: https://viavid.webcasts.com/starthere.jsp?ei=1706029&tp_key=b177e95e36

An archive of the webcast will be available within 24 hours after completion of the live event and will be accessible on the Investor Relations section of the Company's website at www.dyadic.com. To access the replay of the webcast, please follow the webcast link above.

About Dyadic Applied BioSolutions

Dyadic Applied BioSolutions is a global biotechnology company that uses its proprietary microbial platforms to produce recombinant proteins that are sold or licensed to partners across the life sciences, food and nutrition, and bio- industrial markets. These high-quality proteins are designed to enable customers to develop more efficient, scalable, and sustainable products. Dyadic's Dapibus™ and C1 expression systems support flexible, cost-effective manufacturing, and are the foundation of a growing portfolio of commercial and partnered programs.

For more information, please visit http://www.dyadic.com.

Safe Harbor Regarding Forward-Looking Statements

This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act and Section 21E of the Exchange Act, including those regarding Dyadic International's expectations, intentions, strategies, and beliefs pertaining to future events or future financial performance, such as the success of our clinical trial and interest in our protein production platforms, our research projects and third-party collaborations, as well as the availability of necessary funding. Forward-looking statements involve many risks, uncertainties or other factors beyond Dyadic's control. These factors include, but are not limited to, the following: (i) our history of net losses; (ii) market and regulatory acceptance of our microbial protein production platforms and other technologies; (iii) failure to commercialize our microbial protein production platforms or our other technologies; (iv) competition, including from alternative technologies; (v) the results of nonclinical studies and clinical trials; (vi) our capital needs; (vii) changes in global economic and financial conditions; (viii) our reliance on information technology; (ix) our dependence on third parties; (x) government regulations and environmental, social and governance issues; (xi) intellectual property risks; and (xii) our ability to comply with the listing standards of the Nasdaq Stock Market LLC. For a more complete description of the risks that could cause our actual results to differ from our current expectations, please see the section entitled "Risk Factors" in Dyadic's annual reports on Form 10-K and quarterly reports on Form 10-Q filed with the SEC, as such factors may be updated from time to time in Dyadic's periodic filings with the SEC, which are accessible on the SEC's website and at www.dyadic.com. All forward-looking statements speak only as of the date made, and except as required by applicable law, Dyadic assumes no obligation to publicly update any such forward-looking statements for any reason after the date of this press release to conform these statements to actual results or to changes in our expectations.

Contact:

Dyadic International, Inc.

Ping Rawson

Chief Financial Officer

Phone: (561) 743-8333

Email: ir@dyadic.com  

             
DYADIC INTERNATIONAL, INC. AND SUBSIDIARIES CONSOLIDATED STATEMENTS OF OPERATIONS
             
 Three Months Ended

September 30,
 Nine Months Ended

September 30,
 
 2025 2024 2025 2024 
Revenues:            
Research and development revenue$350,046 $532,500 $746,595 $1,253,013 
Grant revenue 814,571  —  1,528,224  — 
License and milestone revenue —  1,425,000  250,000  1,425,000 
Total revenue 1,164,617  1,957,500  2,524,819  2,678,013 
             
Costs and expenses:            
Costs of research and development revenue 254,753  395,894  529,690  841,805 
Costs of grant revenue 769,250  —  1,405,562  — 
Research and development 571,872  460,241  1,696,230  1,498,593 
General and administrative 1,481,356  1,297,984  4,514,324  4,694,334 
Foreign currency exchange loss 12,755  5,995  35,925  14,044 
Total costs and expenses 3,089,986  2,160,114  8,181,731  7,048,776 
             
Loss from operations (1,925,369) (202,614) (5,656,912) (4,370,763)
             
Other income (expense):            



Interest income 63,467  127,331  201,052  353,245 
Interest expense (85,934) (88,833) (264,633) (199,106)
Interest expense - related party (28,176) (39,344) (76,872) (102,632)
Total other income (expense), net (50,643) (846) (140,453) 112,484 
             
Net loss$(1,976,012)$(203,460)$(5,797,365)$(4,258,279)
             
Basic and diluted net loss per common share$(0.06)$(0.01)$(0.17)$(0.15)
             
Basic and diluted weighted-average common shares outstanding 34,507,530  29,503,143  34,507,530  29,503,143 
             

See Notes to Consolidated Financial Statements in Item 1 of Dyadic's Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on November 12, 2025.

  
DYADIC INTERNATIONAL, INC. AND SUBSIDIARIES

CONSOLIDATED BALANCE SHEETS


 
     
 September 30,

2025

 December 31,

2024

 
 (Unaudited) (Audited) 
Assets      
Current assets:      
Cash and cash equivalents$5,834,510 $6,506,750 
Short-term investment securities 3,098,840  2,756,577 
Restricted cash and cash equivalents 1,321,278  — 
Interest receivable 34,117  24,248 
Accounts receivable 916,574  237,027 
Prepaid expenses and other current assets 339,943  303,066 
Total current assets 11,545,262  9,827,668 
       
Non-current assets:      
Long-term investment securities 64,561  — 
Operating lease right-of-use asset, net 52,401  92,211 
Other assets 10,533  10,396 
Total assets$11,672,757 $9,930,275 
       
Liabilities and stockholders' equity      
Current liabilities:      
Accounts payable$1,208,410 $482,320 
Accrued expenses 1,372,364  970,462 
Deferred research and development obligations 1,337,138  833,813 
Operating lease liability, current portion 48,927  54,249 
Accrued interest 60,000  80,000 
Accrued interest- related party 25,133  27,173 
Total current liabilities 4,051,972  2,448,017 
     
Non-current liabilities:    
Convertible notes, net of issuance costs 2,954,882  3,911,471 
Convertible notes, net of issuance costs - related party 2,058,569  1,065,876 
Operating lease liability, net of current portion —  34,621 



Total liabilities 9,065,423  7,459,985 
       
Commitments and contingencies (Note 5)      
       
Stockholders' equity:      
Preferred stock, $.0001 par value:      
Authorized shares - 5,000,000; none issued and outstanding Common stock, $.001 par value: —  — 
Authorized shares - 100,000,000; issued shares - 48,441,300 and 42,089,301, outstanding shares - 36,187,798 and 29,835,799 as of

September 30, 2025, and December 31, 2024, respectively
 48,442  42,090 
Additional paid-in capital 113,372,652  107,444,595 
Treasury stock, shares held at cost - 12,253,502 (18,929,915) (18,929,915)
Accumulated deficit (91,883,845) (86,086,480)
Total stockholders' equity 2,607,334  2,470,290 
Total liabilities and stockholders' equity$11,672,757 $9,930,275 
       

See Notes to Consolidated Financial Statements in Item 1 of Dyadic's Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on November 12, 2025.



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